The voltammetric microsensor based on a gold microelectrodes and an aptamer for determination of blood protein thrombin has been considered. The surface of the gold microelectrodes and the efficiency of the system have been studied. The chemical modification of the surface of a gold microelectrode with aptamers has been carried out. The thrombin determination method based on the change in the conductivity of the solution of the electroactive compound has been proposed.
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