Development of technical systems for artificial blood purification is one of the promising areas of biomedical engineering. System analysis approach is used to create wearable artificial kidney. Investigation of dialysate regeneration methods and multicriteria selection of regeneration unit structure have been carried out. As a result, a prototype of wearable artificial kidney has been manufactured and tested; both the features of its construction and the main ways of its improvement have been highlighted. The developed apparatus is equal or better in its characteristics than foreign analogues (0.8 g/h urea removal rate, 3.5 kg device mass) and is the immediate prospect for the domestic production of equipment for renal replacement therapy
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